Millionaire in his 50s failed to use his child's blood to "stay forever young"

Earlier this year, Bryan Johnson, 45, an American software developer, took his quest to reverse aging to the next level by undergoing the world's first "cross-generational plasma exchange" with his 17-year-old son Talmage and 70-year-old father Richard.

Johnson's 30-strong team of doctors says the procedure has the potential to reverse age-related brain decline.

Accordingly, Bryan Johnson underwent 6 plasma exchanges from 1 liter of blood donated by his son.

Bryan Johnson (45 years old) finds many ways to hold on to his youth despite controversy.

Specifically, blood from a young donor is extracted into red blood cells, white blood cells, platelets and plasma. The converted plasma is then injected into the recipient with the aim of regenerating body parts to combat aging.

While Johnson injected his son's plasma into his veins, his plasma was also injected into his father's veins to perform the 3-generation experiment.

However, after testing a series of biomarkers from his blood, Mr. Johnson concluded that the therapy “did not work,” on July 9. The man did not provide specific information about why the method failed. Meanwhile, Mr. Richard’s results are still pending.

In January, Johnson made headlines for spending millions on anti-aging measures under the name "Project Blueprint." The program includes a strict diet, exercise, sleep habits, and more. He undergoes regular blood tests and organ scans to determine whether he is biologically becoming younger.

Plasma transfusions were just one of many controversial procedures Johnson underwent to prolong his life.

Ambrosia, a California startup that sold rejuvenating plasma for $8,000 a liter, began in 2017. However, the company shut down in 2019, after the US Food and Drug Administration (FDA) warned about the risks of the therapy.

"There is currently no clinical evidence that transfusion of plasma donated from young adults can cure, mitigate, treat, or prevent diseases such as cardiovascular disease or Alzheimer's disease," the FDA's 2019 statement said.

According to the FDA, plasma collected from donors must undergo rigorous testing to ensure safety, so rejuvenating plasma transfusions (like the one Mr. Johnson received) are not considered safe or effective.

Plasma transfusions have been used for severe infections, burns and blood disorders, but there is no conclusive evidence that they can fight aging.

“We don’t know enough to say this is a viable treatment for humans,” said Charles Brenner, a biochemist at City of Hope National Medical Center in Los Angeles. “To me, it’s not well-documented and it’s quite dangerous.”

“The search for ways to slow or stop aging is more complex than looking for regenerative factors in the blood,” said Irina M. Conboy from the University of California, Berkeley.

In the wake of the FDA warning, researchers are taking a more measured approach. Rather than trying to reverse aging, they are identifying the molecular factors responsible for the changes seen in parabiosis experiments in hopes of targeting specific aging-related diseases, such as age-related macular degeneration or Alzheimer's disease.

While Johnson tried various ways to return to his 18 years, the young plasma transfusions appeared to be unsuccessful. He said the therapy was discontinued.

Minh Hoa (t/h)

Source: https://www.nguoiduatin.vn/trieu-phu-u50-that-bai-khi-dung-mau-cua-con-de-tre-mai-khong-gia-a616441.html