Groups of people who are 'averse' to guava leaf water

Health benefits of guava leaf water

Vối water is known as a familiar, healthy drink. Dan Tri newspaper quoted Dr. - Traditional Medicine Practitioner Phung Tuan Giang - President of the Vietnam Institute for Research and Development of Traditional Medicine as saying that according to traditional medicine, the vối tree is widely known in the treatment of influenza and some digestive diseases. In addition, vối leaves and flower buds are also used externally to treat inflammatory conditions, including bruises, acne and ulcers.

Below are the pharmacological effects of guava tree:

Anticancer activity

There have been studies on the cytotoxicity of DMC (the main component of guava leaves) on different cancer cell lines with different levels of cytotoxicity. DMC showed the strongest cytotoxicity against the A549 lung cancer cell line.

DMC is also active against many other cancer cell lines such as HepG2 (liver cancer cells), ASK, P-388 and PANC-1 (pancreatic cancer cells). For other cancer cell lines, DMC showed only moderate activity.

Multidrug resistance is one of the major challenges facing cancer chemotherapy.

Concomitant treatment of DMC with other anticancer drugs has been shown to increase drug activity, increase drug accumulation in tumor tissue, and even have a synergistic effect with the drugs when used in drug-resistant cancer cells.

However, further studies, especially in animal models, are needed to clarify the application of DMC in cancer treatment.

Research on the preventive effects of guava on carcinogens is still in its early stages, and more research is needed to draw conclusions about the cancer-preventive benefits of this plant.

Anti-diabetic and anti-obesity activities

There is ample evidence for the anti-diabetic, anti-obesity properties of guava extract and its major constituent (DMC) in both in vitro and in vivo experimental settings.

Myrtle extract was shown to inhibit polysaccharide hydrolyzing enzymes, reduce blood sugar levels, and protect pancreatic islets in a mouse model.

On the other hand, it has the ability to stimulate insulin secretion, increase glucose uptake in differentiated adipocytes, and protect pancreatic islet cells from oxidative stress, cell damage, and glucose toxicity. Furthermore, DMC was also found to reduce lipid accumulation and promote fatty acid oxidation in mice.

Although antidiabetic and antiobesity activities are not therapeutic indications of myrtle in traditional medicine, these research results suggest the potential clinical application of myrtle in combating chronic conditions such as diabetes and obesity.

Guava leaf water is good for health but not everyone can drink it.

Antioxidant activity

With a very high content of phenolic compounds, guava extract shows strong antioxidant effects in various biological experiments.

Fruit extract showed the ability to protect the kidney from cadmium toxicity in a mouse model while guava leaf extract was found to protect endothelial cells and liver cells from damage caused by hydrogen peroxide (a dangerous free radical).

Since antioxidant activity is involved in many pharmacological activities, such as anti-cancer, anti-inflammatory, hepatoprotective, and neuroprotective activities, the strong antioxidant activity may provide research ideas and directions for exploring other pharmacological effects of myrtle.

Anti-influenza activity

One of the most common uses of guava leaves in traditional Vietnamese and Chinese medicine is to treat influenza.

Current studies suggest that C-methylated flavonoids are the compounds responsible for the anti-influenza activity of myrtle extract. The antiviral activity of myrtle has shown very promising results in in vitro studies, especially against influenza viruses (H1N1 and H9N2).

However, published studies only reported pharmacological results in enzymatic and cell biological assays. Therefore, further studies are needed to confirm the anti-influenza effects of this plant in animal models, thereby laying the foundation for clinical trials.

Anti-inflammatory activity

Previous studies have shown potential anti-inflammatory effects of guava leaf extract and DMC, corroborating the plant's traditional uses in folk medicine, e.g., for skin diseases, boils, and mastitis.

The extract of guava leaves and its major flavonoid (DMC) was found to reduce the expression of pro-inflammatory and inflammatory mediators.

People who are super afraid of guava leaf water

Although guava leaf tea is good for health, not everyone can drink it. According to Health & Life Newspaper, Dr. Vu Duy Thanh said that the following groups of people are advised to limit their use of guava leaf tea:

- Thin and weak people: Do not use guava leaf water for people with thin and weak constitution.

- Children and pregnant women: Children under 12 years old should not use guava leaf water because their digestive system is still weak. Pregnant women should not use too much guava leaf water, it is too concentrated, it affects the digestive and excretory systems.

- When hungry: Do not drink guava leaf tea when hungry, because guava leaves stimulate digestion, increase intestinal motility, so drinking on an empty stomach will make your stomach feel uncomfortable.

- People who are taking medication: People who are being treated for illness, using Western medicine or traditional medicine should not drink guava leaf water, because it can reduce the effectiveness of the medicine they are using. If you want to use guava leaves as a drink, you should consult your doctor.

The above are people who are advised not to use guava leaf water. Please limit the use of guava leaf water if you are in the above group of people.

Ha An (Synthesis)

Source: https://vtcnews.vn/nhung-nhom-nguoi-dai-ky-voi-nuoc-voi-ar910029.html