New method makes cancer cells "commit suicide"

SGGP 07/05/2023 07:02

In a world first, researchers at Israel's Tel Aviv University have encoded a toxin produced by bacteria into messenger RNA (mRNA) molecules and delivered the molecules to cancer cells (pictured).

Cancer cells then produce the same toxins (like bacterial toxins), become poisoned, and die in that environment.

The new method developed by scientists is based on the idea of ​​delivering mRNA molecules encoded with bacterial toxins directly to cancer cells. The research team encoded the genetic information of the toxin protein produced by the pseudomonas bacteria into mRNA molecules.

These molecules were then encapsulated in lipid nanoparticles and coated with antibodies to ensure that the toxin would reach the cancer cells. The team injected these lipid nanoparticles into the tumors of mice with melanoma. Results showed that after a single injection, 44%-60% of the cancer cells disappeared.

Source: https://www.sggp.org.vn/phuong-phap-moi-khien-te-bao-ung-thu-tu-sat-post696154.html