Two children with thalassemia major have successfully received allogeneic bone marrow transplants at Hue Central Hospital. On this occasion, the hospital also announced the success of its 40th neuroblastoma transplant.
On December 19, Hue Central Hospital announced the success of the first two allogeneic bone marrow transplants on patients with thalassemia. The two children were cured and discharged from the hospital to return to life in the happy arms of their parents and family.
This is a major step forward in the application of allogeneic stem cell transplantation, marking an important success in the treatment of this disease, opening up many new opportunities for children with thalassemia. This is also the first hospital to successfully perform stem cell transplantation in the Central Highlands region, and the third unit in Vietnam to apply this advanced technique on thalassemia patients.
The medical staff of Hue Central Hospital presented flowers to congratulate the two little angels who successfully received allogeneic bone marrow transplants.
The first patient is HAD (38 months old, from Quang Tri), who was diagnosed with alpha-thalassemia a year ago and has had to be hospitalized for monthly blood transfusions. After HLA testing, he was confirmed to be a complete match with his 8-year-old brother. He underwent a bone marrow transplant on November 12. After the transplant, platelets recovered on the 10th day and granulocytes recovered on the 19th day.
The second case is D.MAT (10 years old, from Da Nang) who was diagnosed with Alpha-Thalassemia at 20 days old. He had to be hospitalized for blood transfusions every month. After HLA testing, he was also a perfect match with his 15-year-old brother and underwent an allogeneic bone marrow transplant on November 27. The transplant was successful, although he had mild neutropenia but recovered quickly. Platelets recovered on day 21 and granulocytes recovered on day 19.
Up to now, the two children have recovered well and have been discharged from the hospital. From now on, the children no longer have to depend on regular blood transfusions or daily iron excretion, and are developing normally like other healthy children.
Stem cell transplant team of Hue Central Hospital with successful allogeneic bone marrow transplant
Allogeneic bone marrow transplantation opens up prospects for children with thalassemia
According to Professor - Doctor Pham Nhu Hiep, Director of Hue Central Hospital, thalassemia is a genetic disease that causes microcytic anemia, seriously affecting the physical and mental development of children.
In severe cases, children must depend on regular blood transfusions, causing iron overload in the body, causing iron accumulation in the body's organs, leading to many difficulties in life.
Allogeneic bone marrow transplantation is considered the optimal treatment method, providing the opportunity for complete recovery for children, helping them to live healthy lives without blood transfusions. The success of allogeneic bone marrow transplantation at Hue Central Hospital not only brings hope to children with congenital hemolytic anemia, but also opens up treatment prospects for other diseases that require allogeneic bone marrow transplantation, such as bone marrow failure, congenital immunodeficiency, and recurrent cancer.
"For allogeneic stem cell transplantation, finding a suitable HLA is a difficult problem. Therefore, in order for the bone marrow transplant process to continue and help many patients with congenital hemolytic anemia, Hue Central Hospital conducts free HLA testing for patients and their families to find a suitable bone marrow donor," said Professor - Doctor Pham Nhu Hiep.
Along with the implementation of allogeneic bone marrow transplantation, Hue Central Hospital continues to perform autologous bone marrow transplantation for patients with high-risk neuroblastoma. The 40th bone marrow transplant was successfully performed on NPQM (4.5 years old, from Tien Giang).
"With autologous stem cell transplantation, it helps prolong the life of children with high-risk neuroblastoma. Hue Central Hospital is the only hospital in the country that has a full range of multimodal treatments for neuroblastoma: chemotherapy, surgery, bone marrow transplantation and radiotherapy," Professor - Doctor Pham Nhu Hiep added.
Source: https://thanhnien.vn/them-2-ca-ghep-tuy-dong-loai-thanh-cong-cho-benh-nhi-tan-mau-bam-sinh-185241219154341806.htm
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