Pustular psoriasis

VnExpressVnExpress26/10/2023


Pustular psoriasis is characterized by red rash with thick, scaly skin and tiny pustules all over the body. If not treated promptly, it can lead to dangerous complications.

The article was professionally consulted by Dr. Dang Thi Ngoc Bich, Dermatology - Cosmetic Dermatology specialist, Tam Anh General Hospital, Ho Chi Minh City.

Pustular psoriasis is a severe variant of psoriasis caused by a disorder of the skin's immune system. This condition accounts for about 1% of psoriasis cases.

Token

- The skin appears red patches with many small white or yellow pus-filled pimples.

- The acne is easily broken, causing pain and itching. After drying, it forms white scales that are easy to peel off.

- Pustular psoriasis of the whole body can appear with symptoms such as fever, fatigue, headache, trembling limbs, loss of appetite, nausea, rapid heartbeat, joint pain, cracked skin...

Pustular psoriasis on the abdomen. Photo: Freepik

Pustular psoriasis causes pain and itching. After the pustules burst, they dry and form white scales that are easy to peel off. Photo: Freepik

Classify

Pustular psoriasis is divided into two forms: localized and diffuse based on clinical manifestations and location of formation.

- Diffuse pustular psoriasis: Pustular rash appears suddenly all over the body, with forms including:

+ Von Zumbusch psoriasis is pustular psoriasis all over the body accompanied by symptoms of fever, joint pain, muscle weakness, headache, dehydration, anemia...

+ Annular psoriasis with circular lesions with crusting at the wound edges.

+ Acute pustular psoriasis usually has no systemic symptoms and resolves spontaneously after a few days.

+ Herpes simplex impetigo is a pustular form of psoriasis that appears in pregnant women.

- Localized pustular psoriasis: Appears on the palms, soles, tips of fingers, toes and nails.

The disease is common in adults, especially those with a history of psoriasis.

Factors that increase the risk of disease:

- Genetics.

- Staphylococcus aureus skin infection.

- Abrupt discontinuation of systemic steroid use.

- Electrolyte imbalance, hypocalcemia.

- Side effects of the drug.

- Pregnant.

- Exposure to ultraviolet rays.

- Stress

- Get some vaccines to prevent tuberculosis and influenza A H1N1.

People who come into contact with the fluid from the wound of a person with pustular psoriasis do not get the disease. People diagnosed with pustular psoriasis need to determine early whether they have von Zumbusch psoriasis, because this type can be fatal.

Diagnosis and treatment

Besides clinical manifestations, pustular psoriasis is diagnosed by the following methods:

- Test the exudate from the wound.

- Skin biopsy (cut a small 3-5mm skin sample and examine it under a microscope to find the cause of the disease).

- Blood test.

- Liver and kidney function tests.

- Measure the concentration of electrolytes and minerals in the blood.

Pustular psoriasis is difficult to treat. Depending on the patient's constitution and the type of psoriasis, there are currently many methods such as:

- Topical medication.

- Biological drugs.

- Immunosuppressants.

Most cases respond well to home treatment under the guidance of a doctor, but some more severe cases require hospitalization. If not treated promptly, pustular psoriasis can cause a number of dangerous complications such as hypocalcemia, malignant hyperthermia (a sudden increase in body temperature accompanied by muscle spasms and rapid heartbeat), liver damage, acute kidney failure, malnutrition, and even death.

Patients should go to a reputable medical facility with a dermatology department to get a suitable and safe treatment plan. Avoid arbitrarily buying topical medications or applying leaves to the wound, which can make the condition worse.

Disease prevention

- Quit smoking.

- Limit alcohol.

- Get enough sleep and eat healthy.

- Protect skin from sunlight.

Thang Vu



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